null

SMILES: OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN3CCC(O)CC3)cc2Cl)C1

InChI Key: InChIKey=NQTWFBDTTDNESN-BHVANESWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482444 (US10919852, Compound TABLE 1.143 | US11708326, Com...) Show SMILES OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN3CCC(O)CC3)cc2Cl)C1 |r| Show InChI InChI=1S/C40H42Cl2N4O5/c41-35-17-28(22-45-13-10-29(47)11-14-45)38(50-25-27-16-26(19-43)20-44-21-27)18-39(35)51-36-9-8-32-31(4-1-5-33(32)36)34-6-2-7-37(40(34)42)49-15-3-12-46-23-30(48)24-46/h1-2,4-7,16-18,20-21,29-30,36,47-48H,3,8-15,22-25H2/t36-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482444 (US10919852, Compound TABLE 1.143 | US11708326, Com...) Show SMILES OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN3CCC(O)CC3)cc2Cl)C1 |r| Show InChI InChI=1S/C40H42Cl2N4O5/c41-35-17-28(22-45-13-10-29(47)11-14-45)38(50-25-27-16-26(19-43)20-44-21-27)18-39(35)51-36-9-8-32-31(4-1-5-33(32)36)34-6-2-7-37(40(34)42)49-15-3-12-46-23-30(48)24-46/h1-2,4-7,16-18,20-21,29-30,36,47-48H,3,8-15,22-25H2/t36-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair