null

SMILES: C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC(O)C3)c2Cl)cc1OCc1cncc(c1)C#N)C(N)=O

InChI Key: InChIKey=KABSADSDVQMPFG-QYBRANBVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482445 (US10919852, Compound TABLE 1.144 | US11708326, Com...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC(O)C3)c2Cl)cc1OCc1cncc(c1)C#N)C(N)=O |r| Show InChI InChI=1S/C39H41Cl2N5O6/c1-23(47)38(39(43)49)45-19-26-14-32(40)36(15-35(26)51-22-25-13-24(16-42)17-44-18-25)52-33-10-9-29-28(5-2-6-30(29)33)31-7-3-8-34(37(31)41)50-12-4-11-46-20-27(48)21-46/h2-3,5-8,13-15,17-18,23,27,33,38,45,47-48H,4,9-12,19-22H2,1H3,(H2,43,49)/t23-,33+,38+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482445 (US10919852, Compound TABLE 1.144 | US11708326, Com...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC(O)C3)c2Cl)cc1OCc1cncc(c1)C#N)C(N)=O |r| Show InChI InChI=1S/C39H41Cl2N5O6/c1-23(47)38(39(43)49)45-19-26-14-32(40)36(15-35(26)51-22-25-13-24(16-42)17-44-18-25)52-33-10-9-29-28(5-2-6-30(29)33)31-7-3-8-34(37(31)41)50-12-4-11-46-20-27(48)21-46/h2-3,5-8,13-15,17-18,23,27,33,38,45,47-48H,4,9-12,19-22H2,1H3,(H2,43,49)/t23-,33+,38+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair