BDBM482447 US10919852, Compound TABLE 1.146

SMILES: OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN3CC[C@@H](O)C3)cc2Cl)C1

InChI Key: InChIKey=RZQDUBRVTTYWTB-CVYDZTKKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death protein 1 (Homo sapiens)	BDBM482447 (US10919852, Compound TABLE 1.146) Show SMILES OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN3CC[C@@H](O)C3)cc2Cl)C1 |r| Show InChI InChI=1S/C39H40Cl2N4O5/c40-34-15-27(20-45-12-10-28(46)21-45)37(49-24-26-14-25(17-42)18-43-19-26)16-38(34)50-35-9-8-31-30(4-1-5-32(31)35)33-6-2-7-36(39(33)41)48-13-3-11-44-22-29(47)23-44/h1-2,4-7,14-16,18-19,28-29,35,46-47H,3,8-13,20-24H2/t28-,35+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021)
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