null

SMILES: OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc2Cl)C1

InChI Key: InChIKey=OVTPZKHJDQMWIG-WJVKJDHCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482448 (US10919852, Compound TABLE 1.147 | US11708326, Com...) Show SMILES OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc2Cl)C1 |r| Show InChI InChI=1S/C40H41Cl2N5O5/c41-34-15-27(20-45-21-28-8-11-39(49)46-28)37(51-24-26-14-25(17-43)18-44-19-26)16-38(34)52-35-10-9-31-30(4-1-5-32(31)35)33-6-2-7-36(40(33)42)50-13-3-12-47-22-29(48)23-47/h1-2,4-7,14-16,18-19,28-29,35,45,48H,3,8-13,20-24H2,(H,46,49)/t28-,35-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482448 (US10919852, Compound TABLE 1.147 | US11708326, Com...) Show SMILES OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc2Cl)C1 |r| Show InChI InChI=1S/C40H41Cl2N5O5/c41-34-15-27(20-45-21-28-8-11-39(49)46-28)37(51-24-26-14-25(17-43)18-44-19-26)16-38(34)52-35-10-9-31-30(4-1-5-32(31)35)33-6-2-7-36(40(33)42)50-13-3-12-47-22-29(48)23-47/h1-2,4-7,14-16,18-19,28-29,35,45,48H,3,8-13,20-24H2,(H,46,49)/t28-,35-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair