null

SMILES: F[C@@H]1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(OCCCN4CCC(F)CC4)c3Cl)cc2OCc2cncc(c2)C#N)C1

InChI Key: InChIKey=FGWOTXVFFFYRCH-XLNFBEDTSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482462   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482462 (US10919852, Compound TABLE 1.161 | US11708326, Com...) Show SMILES F[C@@H]1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(OCCCN4CCC(F)CC4)c3Cl)cc2OCc2cncc(c2)C#N)C1 |r| Show InChI InChI=1S/C41H42Cl2F2N4O3/c42-36-19-29(24-49-16-12-31(45)25-49)39(51-26-28-18-27(21-46)22-47-23-28)20-40(36)52-37-9-8-33-32(4-1-5-34(33)37)35-6-2-7-38(41(35)43)50-17-3-13-48-14-10-30(44)11-15-48/h1-2,4-7,18-20,22-23,30-31,37H,3,8-17,24-26H2/t31-,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482462 (US10919852, Compound TABLE 1.161 | US11708326, Com...) Show SMILES F[C@@H]1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(OCCCN4CCC(F)CC4)c3Cl)cc2OCc2cncc(c2)C#N)C1 |r| Show InChI InChI=1S/C41H42Cl2F2N4O3/c42-36-19-29(24-49-16-12-31(45)25-49)39(51-26-28-18-27(21-46)22-47-23-28)20-40(36)52-37-9-8-33-32(4-1-5-34(33)37)35-6-2-7-38(41(35)43)50-17-3-13-48-14-10-30(44)11-15-48/h1-2,4-7,18-20,22-23,30-31,37H,3,8-17,24-26H2/t31-,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair