null

SMILES: OC1CC2(C1)CN(CCCOc1cccc(c1Cl)-c1cccc3[C@H](CCc13)Oc1cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc1Cl)C2

InChI Key: InChIKey=BZOOMHJIVBAUON-WLFXDIPCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482465 (US10919852, Compound TABLE 1.164 | US11708326, Com...) Show SMILES OC1CC2(C1)CN(CCCOc1cccc(c1Cl)-c1cccc3[C@H](CCc13)Oc1cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc1Cl)C2 |r| Show InChI InChI=1S/C43H45Cl2N5O5/c44-36-15-29(22-48-23-30-8-11-41(52)49-30)39(54-24-28-14-27(19-46)20-47-21-28)16-40(36)55-37-10-9-33-32(4-1-5-34(33)37)35-6-2-7-38(42(35)45)53-13-3-12-50-25-43(26-50)17-31(51)18-43/h1-2,4-7,14-16,20-21,30-31,37,48,51H,3,8-13,17-18,22-26H2,(H,49,52)/t30-,37-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482465 (US10919852, Compound TABLE 1.164 | US11708326, Com...) Show SMILES OC1CC2(C1)CN(CCCOc1cccc(c1Cl)-c1cccc3[C@H](CCc13)Oc1cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc1Cl)C2 |r| Show InChI InChI=1S/C43H45Cl2N5O5/c44-36-15-29(22-48-23-30-8-11-41(52)49-30)39(54-24-28-14-27(19-46)20-47-21-28)16-40(36)55-37-10-9-33-32(4-1-5-34(33)37)35-6-2-7-38(42(35)45)53-13-3-12-50-25-43(26-50)17-31(51)18-43/h1-2,4-7,14-16,20-21,30-31,37,48,51H,3,8-13,17-18,22-26H2,(H,49,52)/t30-,37-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair