null

SMILES: OC1CC2(C1)CN(CCCOc1cccc(c1Cl)-c1cccc3[C@H](CCc13)Oc1cc(OCc3cncc(c3)C#N)c(CN[C@H]3CCC[C@H]3O)cc1Cl)C2

InChI Key: InChIKey=RIILKTCDVZAXMB-VYSOZWTASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482503 (US10919852, Compound TABLE 1.202 | US11708326, Com...) Show SMILES OC1CC2(C1)CN(CCCOc1cccc(c1Cl)-c1cccc3[C@H](CCc13)Oc1cc(OCc3cncc(c3)C#N)c(CN[C@H]3CCC[C@H]3O)cc1Cl)C2 |r| Show InChI InChI=1S/C43H46Cl2N4O5/c44-35-16-29(23-48-36-8-3-9-37(36)51)40(53-24-28-15-27(20-46)21-47-22-28)17-41(35)54-38-12-11-32-31(5-1-6-33(32)38)34-7-2-10-39(42(34)45)52-14-4-13-49-25-43(26-49)18-30(50)19-43/h1-2,5-7,10,15-17,21-22,30,36-38,48,50-51H,3-4,8-9,11-14,18-19,23-26H2/t36-,37+,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482503 (US10919852, Compound TABLE 1.202 | US11708326, Com...) Show SMILES OC1CC2(C1)CN(CCCOc1cccc(c1Cl)-c1cccc3[C@H](CCc13)Oc1cc(OCc3cncc(c3)C#N)c(CN[C@H]3CCC[C@H]3O)cc1Cl)C2 |r| Show InChI InChI=1S/C43H46Cl2N4O5/c44-35-16-29(23-48-36-8-3-9-37(36)51)40(53-24-28-15-27(20-46)21-47-22-28)17-41(35)54-38-12-11-32-31(5-1-6-33(32)38)34-7-2-10-39(42(34)45)52-14-4-13-49-25-43(26-49)18-30(50)19-43/h1-2,5-7,10,15-17,21-22,30,36-38,48,50-51H,3-4,8-9,11-14,18-19,23-26H2/t36-,37+,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair