BDBM482517 US10919852, Compound TABLE 1.216

SMILES: Cc1c(OCCCN2CCCCC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CNC[C@H]2CCC(=O)N2)cc1Cl

InChI Key: InChIKey=RGYDSQNWIXYBNW-DFABAFTESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death protein 1 (Homo sapiens)	BDBM482517 (US10919852, Compound TABLE 1.216) Show SMILES Cc1c(OCCCN2CCCCC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CNC[C@H]2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C45H48ClN5O4/c1-30-36(8-6-11-41(30)53-19-7-18-51-16-3-2-4-17-51)37-9-5-10-39-38(37)13-14-42(39)55-44-24-43(54-29-33-21-31(25-47)20-32(22-33)26-48)34(23-40(44)46)27-49-28-35-12-15-45(52)50-35/h5-6,8-11,20-24,35,42,49H,2-4,7,12-19,27-29H2,1H3,(H,50,52)/t35-,42+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021)
					More data for this Ligand-Target Pair