null

SMILES: CN1CCC(COc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN[C@@H]3CCCC[C@@H]3O)cc2Cl)C1

InChI Key: InChIKey=BOQMRCLDJCGYMG-NGSGOYSCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482540 (US10919852, Compound TABLE 1.239 | US11708326, Com...) Show SMILES CN1CCC(COc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN[C@@H]3CCCC[C@@H]3O)cc2Cl)C1 |r| Show InChI InChI=1S/C41H44Cl2N4O4/c1-47-15-14-26(23-47)24-49-38-11-5-8-33(41(38)43)30-6-4-7-32-31(30)12-13-37(32)51-40-18-39(50-25-28-16-27(19-44)20-45-21-28)29(17-34(40)42)22-46-35-9-2-3-10-36(35)48/h4-8,11,16-18,20-21,26,35-37,46,48H,2-3,9-10,12-15,22-25H2,1H3/t26?,35-,36+,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482540 (US10919852, Compound TABLE 1.239 | US11708326, Com...) Show SMILES CN1CCC(COc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN[C@@H]3CCCC[C@@H]3O)cc2Cl)C1 |r| Show InChI InChI=1S/C41H44Cl2N4O4/c1-47-15-14-26(23-47)24-49-38-11-5-8-33(41(38)43)30-6-4-7-32-31(30)12-13-37(32)51-40-18-39(50-25-28-16-27(19-44)20-45-21-28)29(17-34(40)42)22-46-35-9-2-3-10-36(35)48/h4-8,11,16-18,20-21,26,35-37,46,48H,2-3,9-10,12-15,22-25H2,1H3/t26?,35-,36+,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair