null

SMILES: O[C@@H]1CC[C@H]1NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC4(CC(F)C4)C3)c2Cl)cc1OCc1cncc(c1)C#N

InChI Key: InChIKey=OQPKODVIZVTELX-RQOYOAKWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482559 (US10919852, Compound TABLE 1.258 | US11708326, Com...) Show SMILES O[C@@H]1CC[C@H]1NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC4(CC(F)C4)C3)c2Cl)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C42H43Cl2FN4O4/c43-34-15-28(22-48-35-9-10-36(35)50)39(52-23-27-14-26(19-46)20-47-21-27)16-40(34)53-37-11-8-31-30(4-1-5-32(31)37)33-6-2-7-38(41(33)44)51-13-3-12-49-24-42(25-49)17-29(45)18-42/h1-2,4-7,14-16,20-21,29,35-37,48,50H,3,8-13,17-18,22-25H2/t35-,36-,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482559 (US10919852, Compound TABLE 1.258 | US11708326, Com...) Show SMILES O[C@@H]1CC[C@H]1NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC4(CC(F)C4)C3)c2Cl)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C42H43Cl2FN4O4/c43-34-15-28(22-48-35-9-10-36(35)50)39(52-23-27-14-26(19-46)20-47-21-27)16-40(34)53-37-11-8-31-30(4-1-5-32(31)37)33-6-2-7-38(41(33)44)51-13-3-12-49-24-42(25-49)17-29(45)18-42/h1-2,4-7,14-16,20-21,29,35-37,48,50H,3,8-13,17-18,22-25H2/t35-,36-,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair