null

SMILES: CN1CCC(COc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc2Cl)C1

InChI Key: InChIKey=MLENBDXMDJTVCC-VEIYQESYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482572 (US10919852, Compound TABLE 1.271 | US11708326, Com...) Show SMILES CN1CCC(COc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc2Cl)C1 |r| Show InChI InChI=1S/C40H41Cl2N5O4/c1-47-13-12-25(22-47)23-49-36-7-3-6-33(40(36)42)30-4-2-5-32-31(30)9-10-35(32)51-38-16-37(50-24-27-14-26(17-43)18-44-19-27)28(15-34(38)41)20-45-21-29-8-11-39(48)46-29/h2-7,14-16,18-19,25,29,35,45H,8-13,20-24H2,1H3,(H,46,48)/t25?,29-,35-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482572 (US10919852, Compound TABLE 1.271 | US11708326, Com...) Show SMILES CN1CCC(COc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNC[C@@H]3CCC(=O)N3)cc2Cl)C1 |r| Show InChI InChI=1S/C40H41Cl2N5O4/c1-47-13-12-25(22-47)23-49-36-7-3-6-33(40(36)42)30-4-2-5-32-31(30)9-10-35(32)51-38-16-37(50-24-27-14-26(17-43)18-44-19-27)28(15-34(38)41)20-45-21-29-8-11-39(48)46-29/h2-7,14-16,18-19,25,29,35,45H,8-13,20-24H2,1H3,(H,46,48)/t25?,29-,35-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair