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SMILES: Cc1c(OCCCN2CCCC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@H]2CCC(=O)NC2)cc1Cl

InChI Key: InChIKey=BXNOLKCPYNATFB-GVICWXJLSA-N

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482590   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482590
PNG
(US10919852, Compound TABLE 1.289)
Show SMILES Cc1c(OCCCN2CCCC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@H]2CCC(=O)NC2)cc1Cl |r|
Show InChI InChI=1S/C44H46ClN5O4/c1-29-35(7-5-10-40(29)52-18-6-17-50-15-2-3-16-50)36-8-4-9-38-37(36)12-13-41(38)54-43-23-42(53-28-32-20-30(24-46)19-31(21-32)25-47)33(22-39(43)45)26-48-34-11-14-44(51)49-27-34/h4-5,7-10,19-23,34,41,48H,2-3,6,11-18,26-28H2,1H3,(H,49,51)/t34-,41-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)

More data for this
Ligand-Target Pair