null

SMILES: CC1CCC(C)N1CCCOc1cccc(c1C)-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@H]2CCC(=O)NC2)cc1Cl

InChI Key: InChIKey=MBVAGARUTDXBQO-KVHSLDQSSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482605 (US10919852, Compound TABLE 1.304 | US11708326, Com...) Show SMILES CC1CCC(C)N1CCCOc1cccc(c1C)-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@H]2CCC(=O)NC2)cc1Cl |r| Show InChI InChI=1S/C46H50ClN5O4/c1-29-11-12-30(2)52(29)17-6-18-54-42-10-5-7-37(31(42)3)38-8-4-9-40-39(38)14-15-43(40)56-45-23-44(55-28-34-20-32(24-48)19-33(21-34)25-49)35(22-41(45)47)26-50-36-13-16-46(53)51-27-36/h4-5,7-10,19-23,29-30,36,43,50H,6,11-18,26-28H2,1-3H3,(H,51,53)/t29?,30?,36-,43-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482605 (US10919852, Compound TABLE 1.304 | US11708326, Com...) Show SMILES CC1CCC(C)N1CCCOc1cccc(c1C)-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@H]2CCC(=O)NC2)cc1Cl |r| Show InChI InChI=1S/C46H50ClN5O4/c1-29-11-12-30(2)52(29)17-6-18-54-42-10-5-7-37(31(42)3)38-8-4-9-40-39(38)14-15-43(40)56-45-23-44(55-28-34-20-32(24-48)19-33(21-34)25-49)35(22-41(45)47)26-50-36-13-16-46(53)51-27-36/h4-5,7-10,19-23,29-30,36,43,50H,6,11-18,26-28H2,1-3H3,(H,51,53)/t29?,30?,36-,43-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair