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SMILES: CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC3(C)C)c2C)c(Cl)cc1CN(C)CCCCC(=O)OC

InChI Key: InChIKey=XJPVFILZFBJWLI-BHVANESWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482715   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482715
PNG
(US10919852, Compound TABLE 1.414)
Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC3(C)C)c2C)c(Cl)cc1CN(C)CCCCC(=O)OC |r|
Show InChI InChI=1S/C40H53ClN2O5/c1-7-46-37-26-38(34(41)25-29(37)27-42(5)21-9-8-17-39(44)45-6)48-36-19-18-32-31(14-10-15-33(32)36)30-13-11-16-35(28(30)2)47-24-12-22-43-23-20-40(43,3)4/h10-11,13-16,25-26,36H,7-9,12,17-24,27H2,1-6H3/t36-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 253n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)

More data for this
Ligand-Target Pair