null
SMILES: CCCCOc1nc(N)c2nc(O)n(Cc3cnc(CNCC4COC4)cn3)c2n1
InChI Key: InChIKey=CMKZFUQFJASHBR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM483318![]() (US10919895, Compound Ia-02) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ... | US Patent US10919895 (2021) BindingDB Entry DOI: 10.7270/Q2KS6VNZ | |||||||||||
More data for this Ligand-Target Pair |