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SMILES: CCCCNCc1cnc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)cn1

InChI Key: InChIKey=XSUXNQGJDIWOFY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM483325 (US10919895, Compound Ia-09) Show SMILES CCCCNCc1cnc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)cn1 Show InChI InChI=1S/C19H28N8O2/c1-3-5-7-21-9-13-10-23-14(11-22-13)12-27-17-15(24-19(27)28)16(20)25-18(26-17)29-8-6-4-2/h10-11,21H,3-9,12H2,1-2H3,(H,24,28)(H2,20,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10919895 (2021)
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM483325 (US10919895, Compound Ia-09) Show SMILES CCCCNCc1cnc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)cn1 Show InChI InChI=1S/C19H28N8O2/c1-3-5-7-21-9-13-10-23-14(11-22-13)12-27-17-15(24-19(27)28)16(20)25-18(26-17)29-8-6-4-2/h10-11,21H,3-9,12H2,1-2H3,(H,24,28)(H2,20,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...				US Patent US10919895 (2021)
					More data for this Ligand-Target Pair