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SMILES: CCCCOc1nc(N)c2nc(O)n(Cc3cnc(CNCCN)cn3)c2n1

InChI Key: InChIKey=QUFMGHLSODASFB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 483327   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))		BDBM483327
PNG
(US10919895, Compound Ia-11)
Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3cnc(CNCCN)cn3)c2n1
Show InChI InChI=1S/C17H25N9O2/c1-2-3-6-28-16-24-14(19)13-15(25-16)26(17(27)23-13)10-12-9-21-11(8-22-12)7-20-5-4-18/h8-9,20H,2-7,10,18H2,1H3,(H,23,27)(H2,19,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 770n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...

US Patent US10919895 (2021)

More data for this
Ligand-Target Pair