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SMILES: CCCCNCc1ccc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)nc1

InChI Key: InChIKey=YHEVTZTZXHJQJW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM483329 (US10919895, Compound Ib-01) Show SMILES CCCCNCc1ccc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)nc1 Show InChI InChI=1S/C20H29N7O2/c1-3-5-9-22-11-14-7-8-15(23-12-14)13-27-18-16(24-20(27)28)17(21)25-19(26-18)29-10-6-4-2/h7-8,12,22H,3-6,9-11,13H2,1-2H3,(H,24,28)(H2,21,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	77	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10919895 (2021)
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM483329 (US10919895, Compound Ib-01) Show SMILES CCCCNCc1ccc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)nc1 Show InChI InChI=1S/C20H29N7O2/c1-3-5-9-22-11-14-7-8-15(23-12-14)13-27-18-16(24-20(27)28)17(21)25-19(26-18)29-10-6-4-2/h7-8,12,22H,3-6,9-11,13H2,1-2H3,(H,24,28)(H2,21,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...				US Patent US10919895 (2021)
					More data for this Ligand-Target Pair