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SMILES: CCCCOc1nc(N)c2nc(O)n(Cc3ccc(CNC4CCC4)cn3)c2n1

InChI Key: InChIKey=KECUIMDMAGUDAD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM483332 (US10919895, Compound Ib-04) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(CNC4CCC4)cn3)c2n1 Show InChI InChI=1S/C20H27N7O2/c1-2-3-9-29-19-25-17(21)16-18(26-19)27(20(28)24-16)12-15-8-7-13(11-23-15)10-22-14-5-4-6-14/h7-8,11,14,22H,2-6,9-10,12H2,1H3,(H,24,28)(H2,21,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10919895 (2021)
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM483332 (US10919895, Compound Ib-04) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(CNC4CCC4)cn3)c2n1 Show InChI InChI=1S/C20H27N7O2/c1-2-3-9-29-19-25-17(21)16-18(26-19)27(20(28)24-16)12-15-8-7-13(11-23-15)10-22-14-5-4-6-14/h7-8,11,14,22H,2-6,9-10,12H2,1H3,(H,24,28)(H2,21,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...				US Patent US10919895 (2021)
					More data for this Ligand-Target Pair