Found 4 hits for monomerid = 484614 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM484614
(US10934297, Compound 8 | US11713320, Compound 8)Show SMILES Cn1cc(cn1)-c1ccc2[nH]nc(C(=O)NCC3CCC(F)(F)CC3)c2c1 Show InChI InChI=1S/C19H21F2N5O/c1-26-11-14(10-23-26)13-2-3-16-15(8-13)17(25-24-16)18(27)22-9-12-4-6-19(20,21)7-5-12/h2-3,8,10-12H,4-7,9H2,1H3,(H,22,27)(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Samumed, LLC
US Patent
| Assay Description
DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response... |
US Patent US10934297 (2021)
BindingDB Entry DOI: 10.7270/Q23N26GM |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM484614
(US10934297, Compound 8 | US11713320, Compound 8)Show SMILES Cn1cc(cn1)-c1ccc2[nH]nc(C(=O)NCC3CCC(F)(F)CC3)c2c1 Show InChI InChI=1S/C19H21F2N5O/c1-26-11-14(10-23-26)13-2-3-16-15(8-13)17(25-24-16)18(27)22-9-12-4-6-19(20,21)7-5-12/h2-3,8,10-12H,4-7,9H2,1H3,(H,22,27)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q20P144B |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM484614
(US10934297, Compound 8 | US11713320, Compound 8)Show SMILES Cn1cc(cn1)-c1ccc2[nH]nc(C(=O)NCC3CCC(F)(F)CC3)c2c1 Show InChI InChI=1S/C19H21F2N5O/c1-26-11-14(10-23-26)13-2-3-16-15(8-13)17(25-24-16)18(27)22-9-12-4-6-19(20,21)7-5-12/h2-3,8,10-12H,4-7,9H2,1H3,(H,22,27)(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q20P144B |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM484614
(US10934297, Compound 8 | US11713320, Compound 8)Show SMILES Cn1cc(cn1)-c1ccc2[nH]nc(C(=O)NCC3CCC(F)(F)CC3)c2c1 Show InChI InChI=1S/C19H21F2N5O/c1-26-11-14(10-23-26)13-2-3-16-15(8-13)17(25-24-16)18(27)22-9-12-4-6-19(20,21)7-5-12/h2-3,8,10-12H,4-7,9H2,1H3,(H,22,27)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Samumed, LLC
US Patent
| Assay Description
GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo... |
US Patent US10934297 (2021)
BindingDB Entry DOI: 10.7270/Q23N26GM |
More data for this
Ligand-Target Pair | |
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