Found 4 hits for monomerid = 484645 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM484645
(US10934297, Compound 39 | US11713320, Compound 39)Show SMILES CCn1cc(cn1)-c1ccc2[nH]nc(C(=O)NC3CCN(CC(C)(C)F)CC3)c2c1 Show InChI InChI=1S/C22H29FN6O/c1-4-29-13-16(12-24-29)15-5-6-19-18(11-15)20(27-26-19)21(30)25-17-7-9-28(10-8-17)14-22(2,3)23/h5-6,11-13,17H,4,7-10,14H2,1-3H3,(H,25,30)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Samumed, LLC
US Patent
| Assay Description
DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response... |
US Patent US10934297 (2021)
BindingDB Entry DOI: 10.7270/Q23N26GM |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM484645
(US10934297, Compound 39 | US11713320, Compound 39)Show SMILES CCn1cc(cn1)-c1ccc2[nH]nc(C(=O)NC3CCN(CC(C)(C)F)CC3)c2c1 Show InChI InChI=1S/C22H29FN6O/c1-4-29-13-16(12-24-29)15-5-6-19-18(11-15)20(27-26-19)21(30)25-17-7-9-28(10-8-17)14-22(2,3)23/h5-6,11-13,17H,4,7-10,14H2,1-3H3,(H,25,30)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | n/a | 33 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q20P144B |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM484645
(US10934297, Compound 39 | US11713320, Compound 39)Show SMILES CCn1cc(cn1)-c1ccc2[nH]nc(C(=O)NC3CCN(CC(C)(C)F)CC3)c2c1 Show InChI InChI=1S/C22H29FN6O/c1-4-29-13-16(12-24-29)15-5-6-19-18(11-15)20(27-26-19)21(30)25-17-7-9-28(10-8-17)14-22(2,3)23/h5-6,11-13,17H,4,7-10,14H2,1-3H3,(H,25,30)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q20P144B |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM484645
(US10934297, Compound 39 | US11713320, Compound 39)Show SMILES CCn1cc(cn1)-c1ccc2[nH]nc(C(=O)NC3CCN(CC(C)(C)F)CC3)c2c1 Show InChI InChI=1S/C22H29FN6O/c1-4-29-13-16(12-24-29)15-5-6-19-18(11-15)20(27-26-19)21(30)25-17-7-9-28(10-8-17)14-22(2,3)23/h5-6,11-13,17H,4,7-10,14H2,1-3H3,(H,25,30)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 33 | n/a | n/a | n/a | n/a |
Samumed, LLC
US Patent
| Assay Description
GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo... |
US Patent US10934297 (2021)
BindingDB Entry DOI: 10.7270/Q23N26GM |
More data for this
Ligand-Target Pair | |
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