null

SMILES: Fc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(c2)C2CCNCC2)cc1

InChI Key: InChIKey=UDYQFVDALPHARI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM484655 (US10934297, Compound 48) Show SMILES Fc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(c2)C2CCNCC2)cc1 Show InChI InChI=1S/C22H21FN6O/c23-16-2-4-17(5-3-16)26-22(30)21-19-11-14(1-6-20(19)27-28-21)15-12-25-29(13-15)18-7-9-24-10-8-18/h1-6,11-13,18,24H,7-10H2,(H,26,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...				US Patent US10934297 (2021) BindingDB Entry DOI: 10.7270/Q23N26GM
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484655 (US10934297, Compound 48) Show SMILES Fc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(c2)C2CCNCC2)cc1 Show InChI InChI=1S/C22H21FN6O/c23-16-2-4-17(5-3-16)26-22(30)21-19-11-14(1-6-20(19)27-28-21)15-12-25-29(13-15)18-7-9-24-10-8-18/h1-6,11-13,18,24H,7-10H2,(H,26,30)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...				US Patent US10934297 (2021) BindingDB Entry DOI: 10.7270/Q23N26GM
					More data for this Ligand-Target Pair