null

SMILES: C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccn5)cc4)c(=O)[nH]c1c23

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 485600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485600 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(4-(py...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccn5)cc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485600 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(4-(py...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccn5)cc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.17	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair