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SMILES: FC(F)(F)c1c(cnn1-c1cncc2ccccc12)C(=O)Nc1cnc(c(c1)C#N)-n1nccn1

InChI Key: InChIKey=HZFYVFLNNOKMBR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487625   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM487625
PNG
(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Show SMILES FC(F)(F)c1c(cnn1-c1cncc2ccccc12)C(=O)Nc1cnc(c(c1)C#N)-n1nccn1
Show InChI InChI=1S/C22H12F3N9O/c23-22(24,25)19-17(11-31-33(19)18-12-27-9-13-3-1-2-4-16(13)18)21(35)32-15-7-14(8-26)20(28-10-15)34-29-5-6-30-34/h1-7,9-12H,(H,32,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)

More data for this
Ligand-Target Pair