null
SMILES: FC(F)(F)c1c(cnn1-c1cccc2ncccc12)C(=O)Nc1cnc(-c2ncco2)c(Cl)c1
InChI Key: InChIKey=VMZLQUHCGKYNGZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human)) | BDBM487669 (N-(5-chloro-6-(oxazol-2- yl)pyridin-3-yl)-1-(quino...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu... | US Patent US10954214 (2021) | |||||||||||
More data for this Ligand-Target Pair |