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SMILES: Cc1nc(c(Cl)cc1NC(=O)c1cnn(c1C(F)(F)F)-c1cccc2c1cc[nH]c2=O)-n1nccn1

InChI Key: InChIKey=BLNWNJATKRGWAJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487690   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM487690
PNG
(N-(5-chloro-2-methyl-6-(2H- 1,2,3-triazol-2-yl)pyr...)
Show SMILES Cc1nc(c(Cl)cc1NC(=O)c1cnn(c1C(F)(F)F)-c1cccc2c1cc[nH]c2=O)-n1nccn1
Show InChI InChI=1S/C22H14ClF3N8O2/c1-11-16(9-15(23)19(31-11)34-28-7-8-29-34)32-21(36)14-10-30-33(18(14)22(24,25)26)17-4-2-3-13-12(17)5-6-27-20(13)35/h2-10H,1H3,(H,27,35)(H,32,36)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 17n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)

More data for this
Ligand-Target Pair