BDBM487692 1-(benzo[d]thiazol-7-yl)-N-(5- cyano-6-(2H-1,2,3-triazol-2- yl)pyridin-3-yl)-5- (trifluoromethyl)-1H-pyrazole-4- carboxamide::US10954214, Compound 114

SMILES: FC(F)(F)c1c(cnn1-c1cccc2ncsc12)C(=O)Nc1cnc(c(c1)C#N)-n1nccn1

InChI Key: InChIKey=QHTZGYNNULRNNL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487692 (1-(benzo[d]thiazol-7-yl)-N-(5- cyano-6-(2H-1,2,3-t...) Show SMILES FC(F)(F)c1c(cnn1-c1cccc2ncsc12)C(=O)Nc1cnc(c(c1)C#N)-n1nccn1 Show InChI InChI=1S/C20H10F3N9OS/c21-20(22,23)17-13(9-29-31(17)15-3-1-2-14-16(15)34-10-26-14)19(33)30-12-6-11(7-24)18(25-8-12)32-27-4-5-28-32/h1-6,8-10H,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021)
					More data for this Ligand-Target Pair