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SMILES: OCc1cnn(n1)-c1ncc(NC(=O)c2cnn(c2C(F)(F)F)-c2cccc3c2cc[nH]c3=O)cc1Cl

InChI Key: InChIKey=XBKHCCQHLHYLHY-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487693   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM487693
PNG
(N-(5-chloro-6-(4- (hydroxymethyl)-2H-1,2,3- triazo...)
Show SMILES OCc1cnn(n1)-c1ncc(NC(=O)c2cnn(c2C(F)(F)F)-c2cccc3c2cc[nH]c3=O)cc1Cl
Show InChI InChI=1S/C22H14ClF3N8O3/c23-16-6-11(7-28-19(16)34-30-8-12(10-35)32-34)31-21(37)15-9-29-33(18(15)22(24,25)26)17-3-1-2-14-13(17)4-5-27-20(14)36/h1-9,35H,10H2,(H,27,36)(H,31,37)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)

More data for this
Ligand-Target Pair