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SMILES: Fc1cccc2c(cncc12)-n1ncc(C(=O)Nc2cnc(c(Cl)c2)-n2nccn2)c1C(F)(F)F

InChI Key: InChIKey=XGVDTIUVGNHTND-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487695   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM487695
PNG
(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Show SMILES Fc1cccc2c(cncc12)-n1ncc(C(=O)Nc2cnc(c(Cl)c2)-n2nccn2)c1C(F)(F)F
Show InChI InChI=1S/C21H11ClF4N8O/c22-15-6-11(7-28-19(15)34-29-4-5-30-34)32-20(35)14-9-31-33(18(14)21(24,25)26)17-10-27-8-13-12(17)2-1-3-16(13)23/h1-10H,(H,32,35)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)

More data for this
Ligand-Target Pair