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SMILES: Fc1cccc2c(cncc12)-n1ncc(C(=O)Nc2cnc(c(c2)C#N)-n2nccn2)c1C(F)(F)F

InChI Key: InChIKey=QDGXCQVHDMNGDJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487696   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM487696
PNG
(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Show SMILES Fc1cccc2c(cncc12)-n1ncc(C(=O)Nc2cnc(c(c2)C#N)-n2nccn2)c1C(F)(F)F
Show InChI InChI=1S/C22H11F4N9O/c23-17-3-1-2-14-15(17)9-28-11-18(14)34-19(22(24,25)26)16(10-32-34)21(36)33-13-6-12(7-27)20(29-8-13)35-30-4-5-31-35/h1-6,8-11H,(H,33,36)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)

More data for this
Ligand-Target Pair