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SMILES: Nc1ccc(-n2ncc(C(=O)Nc3cnc(c(c3)C#N)-n3nccn3)c2C(F)(F)F)c2ccccc12

InChI Key: InChIKey=YIEJKWLLHDBWNT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487710   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM487710
PNG
(1-(4-aminonaphthalen-1-yl)-N- (5-cyano-6-(2H-1,2,3...)
Show SMILES Nc1ccc(-n2ncc(C(=O)Nc3cnc(c(c3)C#N)-n3nccn3)c2C(F)(F)F)c2ccccc12
Show InChI InChI=1S/C23H14F3N9O/c24-23(25,26)20-17(12-32-34(20)19-6-5-18(28)15-3-1-2-4-16(15)19)22(36)33-14-9-13(10-27)21(29-11-14)35-30-7-8-31-35/h1-9,11-12H,28H2,(H,33,36)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)

More data for this
Ligand-Target Pair