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SMILES: COC(=O)c1ncc(NC(=O)c2cnn(c2C(F)(F)F)-c2cccc3c2cc[nH]c3=O)cc1Cl

InChI Key: InChIKey=WBGQQCPDPWJUTH-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487933   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM487933
PNG
(US10954214, Compound 355 | methyl 3-chloro-5-(1-(1...)
Show SMILES COC(=O)c1ncc(NC(=O)c2cnn(c2C(F)(F)F)-c2cccc3c2cc[nH]c3=O)cc1Cl
Show InChI InChI=1S/C21H13ClF3N5O4/c1-34-20(33)16-14(22)7-10(8-27-16)29-19(32)13-9-28-30(17(13)21(23,24)25)15-4-2-3-12-11(15)5-6-26-18(12)31/h2-9H,1H3,(H,26,31)(H,29,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)

More data for this
Ligand-Target Pair