null
SMILES: OC1CN(C1)c1ncc(-n2ncc(C(=O)Nc3cnc(c(Cl)c3)-n3nccn3)c2C(F)(F)F)c2ccsc12
InChI Key: InChIKey=ILLCANPYIRYMAG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human)) | BDBM488008![]() (N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu... | US Patent US10954214 (2021) | |||||||||||
More data for this Ligand-Target Pair |