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SMILES: FC(F)(F)c1c(cnn1-c1ccnc2ccccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1

InChI Key: InChIKey=FQDJYHQMCYEJRT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488028   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM488028
PNG
(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Show SMILES FC(F)(F)c1c(cnn1-c1ccnc2ccccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1
Show InChI InChI=1S/C21H12ClF3N8O/c22-15-9-12(10-27-19(15)33-28-7-8-29-33)31-20(34)14-11-30-32(18(14)21(23,24)25)17-5-6-26-16-4-2-1-3-13(16)17/h1-11H,(H,31,34)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)

More data for this
Ligand-Target Pair