null

SMILES: COc1cccc(c1)-c1cc(F)cc(c1)-c1nn(c(CC2CC2)c1Cc1ccc(cc1)S(N)(=O)=O)-c1nc(cs1)C(O)=O

InChI Key: InChIKey=NYQSNNBWIBWRRQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
L-lactate dehydrogenase A chain (Homo sapiens (Human))	BDBM489097 (2-(5- (cyclopropylmethyl)- 3-(5-fluoro-3'- methoxy...) Show SMILES COc1cccc(c1)-c1cc(F)cc(c1)-c1nn(c(CC2CC2)c1Cc1ccc(cc1)S(N)(=O)=O)-c1nc(cs1)C(O)=O Show InChI InChI=1S/C31H27FN4O5S2/c1-41-24-4-2-3-20(16-24)21-13-22(15-23(32)14-21)29-26(11-18-7-9-25(10-8-18)43(33,39)40)28(12-19-5-6-19)36(35-29)31-34-27(17-42-31)30(37)38/h2-4,7-10,13-17,19H,5-6,11-12H2,1H3,(H,37,38)(H2,33,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98TV
					More data for this Ligand-Target Pair
L-lactate dehydrogenase A chain (Homo sapiens (Human))	BDBM489097 (2-(5- (cyclopropylmethyl)- 3-(5-fluoro-3'- methoxy...) Show SMILES COc1cccc(c1)-c1cc(F)cc(c1)-c1nn(c(CC2CC2)c1Cc1ccc(cc1)S(N)(=O)=O)-c1nc(cs1)C(O)=O Show InChI InChI=1S/C31H27FN4O5S2/c1-41-24-4-2-3-20(16-24)21-13-22(15-23(32)14-21)29-26(11-18-7-9-25(10-8-18)43(33,39)40)28(12-19-5-6-19)36(35-29)31-34-27(17-42-31)30(37)38/h2-4,7-10,13-17,19H,5-6,11-12H2,1H3,(H,37,38)(H2,33,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; VANDERBILT UNIVERSITY; THE UAB RESEARCH FOUNDATION; THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...				US Patent US10961200 (2021) BindingDB Entry DOI: 10.7270/Q2474DZ9
					More data for this Ligand-Target Pair