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SMILES: CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)c3ccccc3)cccc12

InChI Key: InChIKey=BOZYUIQTTVFWDX-SANMLTNESA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490012   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM490012
PNG
((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...)
Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)c3ccccc3)cccc12 |r|
Show InChI InChI=1S/C30H31N3O5S/c1-30(2,3)33-39(37,38)27-14-8-11-23-24(27)12-7-13-25(23)31-29(36)26(19-20-15-17-22(34)18-16-20)32-28(35)21-9-5-4-6-10-21/h4-18,26,33-34H,19H2,1-3H3,(H,31,36)(H,32,35)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 470n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM490012
PNG
((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...)
Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)c3ccccc3)cccc12 |r|
Show InChI InChI=1S/C30H31N3O5S/c1-30(2,3)33-39(37,38)27-14-8-11-23-24(27)12-7-13-25(23)31-29(36)26(19-20-15-17-22(34)18-16-20)32-28(35)21-9-5-4-6-10-21/h4-18,26,33-34H,19H2,1-3H3,(H,31,36)(H,32,35)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 520n/an/an/an/an/an/a



Mitobridge, Inc.

US Patent


Assay Description
The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...


US Patent US10968172 (2021)

More data for this
Ligand-Target Pair