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SMILES: Cc1ccc(C[C@H](NC(=O)c2ccccc2)C(=O)Nc2cccc3c(cccc23)S(=O)(=O)NC(C)(C)C)cc1

InChI Key: InChIKey=XJZDZBZJPVLTAP-MHZLTWQESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490023   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM490023
PNG
((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...)
Show SMILES Cc1ccc(C[C@H](NC(=O)c2ccccc2)C(=O)Nc2cccc3c(cccc23)S(=O)(=O)NC(C)(C)C)cc1 |r|
Show InChI InChI=1S/C31H33N3O4S/c1-21-16-18-22(19-17-21)20-27(33-29(35)23-10-6-5-7-11-23)30(36)32-26-14-8-13-25-24(26)12-9-15-28(25)39(37,38)34-31(2,3)4/h5-19,27,34H,20H2,1-4H3,(H,32,36)(H,33,35)/t27-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM490023
PNG
((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...)
Show SMILES Cc1ccc(C[C@H](NC(=O)c2ccccc2)C(=O)Nc2cccc3c(cccc23)S(=O)(=O)NC(C)(C)C)cc1 |r|
Show InChI InChI=1S/C31H33N3O4S/c1-21-16-18-22(19-17-21)20-27(33-29(35)23-10-6-5-7-11-23)30(36)32-26-14-8-13-25-24(26)12-9-15-28(25)39(37,38)34-31(2,3)4/h5-19,27,34H,20H2,1-4H3,(H,32,36)(H,33,35)/t27-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Mitobridge, Inc.

US Patent


Assay Description
The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...


US Patent US10968172 (2021)

More data for this
Ligand-Target Pair