BindingDB logo
myBDB logout

null

SMILES: CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccccc2)cc1

InChI Key: InChIKey=IACYMAMLWRJMAE-QHCPKHFHSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490025   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM490025
PNG
((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...)
Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccccc2)cc1 |r|
Show InChI InChI=1S/C26H29N3O4S/c1-26(2,3)29-34(32,33)22-16-14-21(15-17-22)27-25(31)23(18-19-10-6-4-7-11-19)28-24(30)20-12-8-5-9-13-20/h4-17,23,29H,18H2,1-3H3,(H,27,31)(H,28,30)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM490025
PNG
((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...)
Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccccc2)cc1 |r|
Show InChI InChI=1S/C26H29N3O4S/c1-26(2,3)29-34(32,33)22-16-14-21(15-17-22)27-25(31)23(18-19-10-6-4-7-11-19)28-24(30)20-12-8-5-9-13-20/h4-17,23,29H,18H2,1-3H3,(H,27,31)(H,28,30)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Mitobridge, Inc.

US Patent


Assay Description
The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...


US Patent US10968172 (2021)

More data for this
Ligand-Target Pair