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SMILES: C[C@H](CO)n1cnnc1-c1cccc(NC(=O)c2cc(C3CC3NC(=O)C(C)(C)C)c(C)cc2F)n1

InChI Key: InChIKey=NMLMVXZZWNUMDA-FPPRHVDESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490119   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 5


(Homo sapiens (Human))		BDBM490119
PNG
(US10968199, Example 29)
Show SMILES C[C@H](CO)n1cnnc1-c1cccc(NC(=O)c2cc(C3CC3NC(=O)C(C)(C)C)c(C)cc2F)n1 |r|
Show InChI InChI=1S/C26H31FN6O3/c1-14-9-19(27)18(10-16(14)17-11-21(17)30-25(36)26(3,4)5)24(35)31-22-8-6-7-20(29-22)23-32-28-13-33(23)15(2)12-34/h6-10,13,15,17,21,34H,11-12H2,1-5H3,(H,30,36)(H,29,31,35)/t15-,17?,21?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.5n/an/an/an/an/an/a



Enanta Pharmaceuticals, Inc.

US Patent


Assay Description
ASK1 was purchased from Thermofisher (Catalogue #PV4011), ATP was purchased from Sigma (Catalogue #A7699), HTRF® KinEASE™ Assay System was obtained f...

US Patent US10968199 (2021)

More data for this
Ligand-Target Pair