BDBM490203 N-(5-methyl-1,2- oxazol-3-yl)-5- ((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- thiophene-3- carboxamide::US10968213, Example 81

SMILES: Cc1cc(NC(=O)c2cc(cs2)[C@@H]2C[C@H]2NCC2CCOCC2)no1

InChI Key: InChIKey=NEEVDAJZAXQIQT-LSDHHAIUSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 490203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM490203 (N-(5-methyl-1,2- oxazol-3-yl)-5- ((1R,2R)-2- ((tet...) Show SMILES Cc1cc(NC(=O)c2cc(cs2)[C@@H]2C[C@H]2NCC2CCOCC2)no1 |r| Show InChI InChI=1S/C18H23N3O3S/c1-11-6-17(21-24-11)20-18(22)16-7-13(10-25-16)14-8-15(14)19-9-12-2-4-23-5-3-12/h6-7,10,12,14-15,19H,2-5,8-9H2,1H3,(H,20,21,22)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description LSD1: A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and...				US Patent US10968213 (2021)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM490203 (N-(5-methyl-1,2- oxazol-3-yl)-5- ((1R,2R)-2- ((tet...) Show SMILES Cc1cc(NC(=O)c2cc(cs2)[C@@H]2C[C@H]2NCC2CCOCC2)no1 |r| Show InChI InChI=1S/C18H23N3O3S/c1-11-6-17(21-24-11)20-18(22)16-7-13(10-25-16)14-8-15(14)19-9-12-2-4-23-5-3-12/h6-7,10,12,14-15,19H,2-5,8-9H2,1H3,(H,20,21,22)/t14-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...				US Patent US10968213 (2021)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM490203 (N-(5-methyl-1,2- oxazol-3-yl)-5- ((1R,2R)-2- ((tet...) Show SMILES Cc1cc(NC(=O)c2cc(cs2)[C@@H]2C[C@H]2NCC2CCOCC2)no1 |r| Show InChI InChI=1S/C18H23N3O3S/c1-11-6-17(21-24-11)20-18(22)16-7-13(10-25-16)14-8-15(14)19-9-12-2-4-23-5-3-12/h6-7,10,12,14-15,19H,2-5,8-9H2,1H3,(H,20,21,22)/t14-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...				US Patent US10968213 (2021)
					More data for this Ligand-Target Pair