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SMILES: Cc1cc(cc(C)n1)-c1nnc(N)nc1-c1ccc(Cl)cc1

InChI Key: InChIKey=FQGPESZLQLSFSS-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493764   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM493764
PNG
(US10988455, Example 1(clix))
Show SMILES Cc1cc(cc(C)n1)-c1nnc(N)nc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H14ClN5/c1-9-7-12(8-10(2)19-9)15-14(20-16(18)22-21-15)11-3-5-13(17)6-4-11/h3-8H,1-2H3,(H2,18,20,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
15.5n/an/an/an/an/an/an/an/a



Heptares Therapeutics Limited

US Patent


Assay Description
All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...


US Patent US10988455 (2021)

More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))
BDBM493764
PNG
(US10988455, Example 1(clix))
Show SMILES Cc1cc(cc(C)n1)-c1nnc(N)nc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H14ClN5/c1-9-7-12(8-10(2)19-9)15-14(20-16(18)22-21-15)11-3-5-13(17)6-4-11/h3-8H,1-2H3,(H2,18,20,22)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
85.1n/an/an/an/an/an/an/an/a



Heptares Therapeutics Limited

US Patent


Assay Description
All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...


US Patent US10988455 (2021)

More data for this
Ligand-Target Pair