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SMILES: C[C@@H]1[C@H](CNC1=O)C(=O)Nc1cc(-c2cc(F)cc(OC(C)(C)C(F)(F)F)c2)n(n1)-c1cccnc1C#N

InChI Key: InChIKey=OQTBPIJFGJRUHB-DYVFJYSZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 493895   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM493895
PNG
(US10988462, Example 11)
Show SMILES C[C@@H]1[C@H](CNC1=O)C(=O)Nc1cc(-c2cc(F)cc(OC(C)(C)C(F)(F)F)c2)n(n1)-c1cccnc1C#N |r|
Show InChI InChI=1S/C25H22F4N6O3/c1-13-17(12-32-22(13)36)23(37)33-21-10-20(35(34-21)19-5-4-6-31-18(19)11-30)14-7-15(26)9-16(8-14)38-24(2,3)25(27,28)29/h4-10,13,17H,12H2,1-3H3,(H,32,36)(H,33,34,37)/t13-,17+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.40n/an/an/an/an/an/a



Japan Tobacco Inc.

US Patent


Assay Description
Human SGLT1-stably-expressing cell lines were seeded at 5×104 cells/well on BioCoat™ Poly-D-Lysine 96 well plate with Lid (Becton, Dickinson and Comp...

US Patent US10988462 (2021)

More data for this
Ligand-Target Pair