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SMILES: C[C@@H]1[C@H](CNC1=O)C(=O)Nc1cc(-c2cc(F)cc(OC(F)(F)F)c2)n(n1)-c1cncnc1

InChI Key: InChIKey=PUEJHRICONVIQS-BMIGLBTASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 493916   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM493916
PNG
(US10988462, Example 29)
Show SMILES C[C@@H]1[C@H](CNC1=O)C(=O)Nc1cc(-c2cc(F)cc(OC(F)(F)F)c2)n(n1)-c1cncnc1 |r|
Show InChI InChI=1S/C20H16F4N6O3/c1-10-15(8-27-18(10)31)19(32)28-17-5-16(30(29-17)13-6-25-9-26-7-13)11-2-12(21)4-14(3-11)33-20(22,23)24/h2-7,9-10,15H,8H2,1H3,(H,27,31)(H,28,29,32)/t10-,15+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 52n/an/an/an/an/an/a



Japan Tobacco Inc.

US Patent


Assay Description
Human SGLT1-stably-expressing cell lines were seeded at 5×104 cells/well on BioCoat™ Poly-D-Lysine 96 well plate with Lid (Becton, Dickinson and Comp...

US Patent US10988462 (2021)

More data for this
Ligand-Target Pair