BindingDB PrimarySearch_ki

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null

SMILES: Oc1ccc2C[C@H]3N(CC[C@@]45C(Oc1c24)[C@@H](CC[C@@]35O)NC(=O)c1c[nH]c2ccccc12)C1CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 494110
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM494110 (US10988481, Compound 11) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University US Patent					Assay Description The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...				US Patent US10988481 (2021)
Virginia Commonwealth University US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM494110 (US10988481, Compound 11) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.192	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University US Patent					Assay Description The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...				US Patent US10988481 (2021)
Virginia Commonwealth University US Patent					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM494110 (US10988481, Compound 11) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University US Patent					Assay Description The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...				US Patent US10988481 (2021)
Virginia Commonwealth University US Patent					More data for this Ligand-Target Pair