BDBM49511 1-[[2-(4-ethoxyphenyl)quinolin-4-yl]carbonylamino]-3-ethyl-thiourea::1-[[2-(4-ethoxyphenyl)quinoline-4-carbonyl]amino]-3-ethylthiourea::1-[[[2-(4-ethoxyphenyl)-4-quinolinyl]-oxomethyl]amino]-3-ethylthiourea::1-ethyl-3-[(2-p-phenetylquinoline-4-carbonyl)amino]thiourea::2-{[2-(4-ethoxyphenyl)-4-quinolinyl]carbonyl}-N-ethylhydrazinecarbothioamide::MLS000545499::SMR000160210::cid_1767610

SMILES: CCNC(=S)NNC(=O)c1cc(nc2ccccc12)-c1ccc(OCC)cc1

InChI Key: InChIKey=OUMOCZYTTNFGNH-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 49511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (Homo sapiens (Human))	BDBM49511 (1-[[2-(4-ethoxyphenyl)quinolin-4-yl]carbonylamino]...) Show SMILES CCNC(=S)NNC(=O)c1cc(nc2ccccc12)-c1ccc(OCC)cc1 Show InChI InChI=1S/C21H22N4O2S/c1-3-22-21(28)25-24-20(26)17-13-19(23-18-8-6-5-7-16(17)18)14-9-11-15(12-10-14)27-4-2/h5-13H,3-4H2,1-2H3,(H,24,26)(H2,22,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27P8WT7
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM49511 (1-[[2-(4-ethoxyphenyl)quinolin-4-yl]carbonylamino]...) Show SMILES CCNC(=S)NNC(=O)c1cc(nc2ccccc12)-c1ccc(OCC)cc1 Show InChI InChI=1S/C21H22N4O2S/c1-3-22-21(28)25-24-20(26)17-13-19(23-18-8-6-5-7-16(17)18)14-9-11-15(12-10-14)27-4-2/h5-13H,3-4H2,1-2H3,(H,24,26)(H2,22,25,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.75E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...				PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2ZP44SP
					More data for this Ligand-Target Pair
Hsf1 protein (Mus musculus)	BDBM49511 (1-[[2-(4-ethoxyphenyl)quinolin-4-yl]carbonylamino]...) Show SMILES CCNC(=S)NNC(=O)c1cc(nc2ccccc12)-c1ccc(OCC)cc1 Show InChI InChI=1S/C21H22N4O2S/c1-3-22-21(28)25-24-20(26)17-13-19(23-18-8-6-5-7-16(17)18)14-9-11-15(12-10-14)27-4-2/h5-13H,3-4H2,1-2H3,(H,24,26)(H2,22,25,28)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX
					More data for this Ligand-Target Pair