US11001563, Compound WX023

SMILES: NC\C(COc1ccc(cc1)-c1nc2ccccc2o1)=C\F

InChI Key: InChIKey=HSDOLWWRACNOBG-XFXZXTDPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM497156 (US11001563, Compound WX023) Show SMILES NC\C(COc1ccc(cc1)-c1nc2ccccc2o1)=C\F Show InChI InChI=1S/C17H15FN2O2/c18-9-12(10-19)11-21-14-7-5-13(6-8-14)17-20-15-3-1-2-4-16(15)22-17/h1-9H,10-11,19H2/b12-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The inhibition of the sample on VAP-enzyme activity was measured by using an Amplex® Red Monoamine Oxidase kit (Invitrogen #A12214). 100 nL of the gr...				US Patent US11001563 (2021)
					More data for this Ligand-Target Pair