US11001563, Compound WX117

SMILES: Cn1nc(nc1-c1ccc(OC\C(CN)=C/F)cc1F)C1(F)CC1

InChI Key: InChIKey=KCMFVKDSHXFUKQ-YFHOEESVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM497217 (US11001563, Compound WX117) Show SMILES Cn1nc(nc1-c1ccc(OC\C(CN)=C/F)cc1F)C1(F)CC1 Show InChI InChI=1S/C16H17F3N4O/c1-23-14(21-15(22-23)16(19)4-5-16)12-3-2-11(6-13(12)18)24-9-10(7-17)8-20/h2-3,6-7H,4-5,8-9,20H2,1H3/b10-7-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The inhibition of the sample on VAP-enzyme activity was measured by using an Amplex® Red Monoamine Oxidase kit (Invitrogen #A12214). 100 nL of the gr...				US Patent US11001563 (2021)
					More data for this Ligand-Target Pair