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SMILES: COCCn1nccc1C(=O)Nc1cc([nH]n1)[C@H]1CC[C@H](C1)OC(=O)NC(C)CC(F)(F)F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 498262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM498262 (US11014911, Example 87 | US11014911, Example 88 | ...) Show SMILES COCCn1nccc1C(=O)Nc1cc([nH]n1)[C@H]1CC[C@H](C1)OC(=O)NC(C)CC(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...				US Patent US11014911 (2021) BindingDB Entry DOI: 10.7270/Q23N26H2
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM498262 (US11014911, Example 87 | US11014911, Example 88 | ...) Show SMILES COCCn1nccc1C(=O)Nc1cc([nH]n1)[C@H]1CC[C@H](C1)OC(=O)NC(C)CC(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22F7SJ2
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM498262 (US11014911, Example 87 | US11014911, Example 88 | ...) Show SMILES COCCn1nccc1C(=O)Nc1cc([nH]n1)[C@H]1CC[C@H](C1)OC(=O)NC(C)CC(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22F7SJ2
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM498262 (US11014911, Example 87 | US11014911, Example 88 | ...) Show SMILES COCCn1nccc1C(=O)Nc1cc([nH]n1)[C@H]1CC[C@H](C1)OC(=O)NC(C)CC(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...				US Patent US11014911 (2021) BindingDB Entry DOI: 10.7270/Q23N26H2
					More data for this Ligand-Target Pair