null
SMILES: Clc1cccc(c1)-c1cc(NC(=O)C[C@H]2CCN(C2)C#N)on1
InChI Key: InChIKey=DSBRXBQUNFFWBD-LLVKDONJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM498860![]() ((R)N-(3-(3-Chlorophenyl)isoxazol-5-yl)-2-(1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US11014912 (2021) | |||||||||||
More data for this Ligand-Target Pair |