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SMILES: C[C@H]([C@@H]1CCN(C1)C#N)C(=O)Nc1cc(no1)-c1cccc(Cl)c1

InChI Key: InChIKey=MLSIFLHNCUDDIH-DGCLKSJQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 498877   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))		BDBM498877
PNG
(US11014912, Example 53)
Show SMILES C[C@H]([C@@H]1CCN(C1)C#N)C(=O)Nc1cc(no1)-c1cccc(Cl)c1
Show InChI InChI=1S/C17H17ClN4O2/c1-11(13-5-6-22(9-13)10-19)17(23)20-16-8-15(21-24-16)12-3-2-4-14(18)7-12/h2-4,7-8,11,13H,5-6,9H2,1H3,(H,20,23)/t11-,13-/m1/s1
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...

US Patent US11014912 (2021)

More data for this
Ligand-Target Pair